Germany scored five times in 27 minutes in the first half to crush Estonia 8-0 and make it three wins in three Euro 2020 Group C qualifiers.
Balotelli made his debut for his hometown club after completing a four-match suspension that he was handed at Olympique de Marseille last season, while the visitors were without Cristiano Ronaldo as he recovers from injury.
Ten-man Manchester City staged a dramatic comeback with late goals from Leroy Sane and Raheem Sterling securing them a 3-2 win at Schalke 04 in their Champions League Round of 16 first leg.
IMAGES from the Euro 2020 qualifiers
A summary of all the Champions League matches played across Europe on Wednesday
Photographic summary of the football matches played across Spain, Italy and France
Cristiano Ronaldo scored twice in his 150th European appearance to give Real Madrid a 3-1 victory at Borussia Dortmund, their first against them in Germany, and make it two wins out of two matches in their Champions League Group H.
Photos from the Champions League matches played across Europe on Tuesday
Images from Champions League matches played across Europe on Tuesday
Football news from Ligue 1, Bundesliga and La liga.
News of all that's transpired on and off the football field
Reigning French Open champion Maria Sharapova, former world number one Venus Williams and Australian Samantha Stosur sailed into the second round of the China Open with straight set victories on Sunday.