The UK Health Security Agency said EG.5.1, which has been nicknamed Eris, makes up one in seven new COVID cases.
The UK reported 93,045 cases of coronavirus on Friday, another record high for daily infections for the third consecutive day, as Omicron overtook Delta to become the dominant variant in London and Scotland.
Tottenham Hotspur recorded 13 COVID-19 cases at the club last week, while Leicester City and Manchester United were also affected by the virus.
A third dose of COVID-19 vaccine can provide up to 88 per cent protection against hospitalisation from infection by the Omicron variant of coronavirus, according to early results from studies conducted in the UK.
Two doses of Pfizer and AstraZeneca COVID-19 vaccines generate lower levels of antibodies against the Omicron variant of coronavirus, according to a study which suggests that those previously infected or vaccinated may be at an increased risk of infection.
There are around 7.5 million people aged 30 to 39, and 3.5 million of those are eligible for boosters from Monday, NHS England said.
The UK Health Security Agency (UKHSA), which monitors data related to the pandemic, said the sub-lineage known as BA.2 shows a low number of cases in the country, with the original Omicron lineage BA.1 still dominant.
The UK Health Security Agency (UKHSA) analysis showed that around three months after the third jab, protection against hospitalisation among those aged 65 and over remains at about 90 per cent.
British Prime Minister Boris Johnson on Monday confirmed the UK's first death from the Omicron variant of coronavirus, the first known fatality from the highly transmissible variant of Covid-19 in the world.
The Delta variant of COVID-19, or the B1.617.2 variant of concern (VOC) first identified in India, is about 60 per cent more transmissible than the Alpha strain identified in the United Kingdom and also reduces the effectiveness of vaccines to some extent, UK health experts report.
The move came soon after Belgium confirmed a case of the B.1.1.529 variant in someone who had travelled back from Egypt earlier this month, with the European Union (EU) member states agreeing to a snap travel ban on seven African nations.
The UK's health authorities have confirmed that a new and "most significant" variant of COVID-19 is officially under investigation in the country as the government on Friday added six countries to its travel ban red list from southern Africa, where B.1.1.529 strain was first identified.
Johnson will instead speak to Prime Minister Narendra Modi later this month to launch their plans for the future UK-India partnership, with their physical meeting expected later in the year.
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