Liverpool face Spurs in the game of the weekend, a day after title rivals Manchester City travel to struggling Fulham.
Manchester United manager Jose Mourinho has dismissed speculation about his future at the Premier League club, saying he would like a long-term stay at Old Trafford provided the team's owners are happy with his input.
New Manchester City manager Pep Guardiola has come to England to prove himself and wants to produce the "beautiful football" for which his teams are famed, he told reporters on Friday. Speaking at his first news conference since joining the club, the former Barcelona and Bayern Munich coach said his personal learning curve would be steep as he came to terms with his new team and adapted to the rigours of the Premier League. "It's the right moment to come here and prove myself," he said. Asked if he could get City to play the sort of beautiful football trademarked by Barcelona, he added. "That's why I am here. I want to play the way I want. But wherever you go you have to adapt to the quality of the players. We have to find each other as soon as possible.
Chelsea's third successive league win lifted them level on 18 points with Leicester City but are top thanks to a better goal difference. Leicester face Liverpool on Sunday.
It was not so much the maths, though Liverpool's nine-point advantage over defending champions City, with one point less over Leicester City and Chelsea, is a significant gap, especially as Juergen Klopp's side have lost one league game in 18 months.
News of all that transpired on and off the football field.
Media reports said former England manager Roy Hodgson was in line to replace De Boer at Selhurst Park.
City will look to extend lead against United at Old Trafford
City, who have dished out a string of maulings in a stellar league campaign, found the Championship side a tough nut to crack and had to wait until the 92nd minute to grab the winner when Argentine substitute Aguero darted in to head home.
'Before the start of the season I felt Manchester United will be a lot better this year and they were my tip for the title'
Manchester City's stellar season gathered yet more momentum as the runaway English Premier League leaders reached the League Cup semi-finals with a penalty shootout victory at Leicester City.
Liverpool will attempt to sweep away the January blues on the last day of a wretched month when they host commanding Premier League leaders Chelsea at Anfield on Tuesday.
News of all that transpired on and off the football field
Manchester City endured some anxious moments but escaped from fourth-tier Newport County with their FA Cup hopes intact as Phil Foden scored twice in an ultimately comfortable 4-1 fifth-round victory on Saturday.
Mohamed Salah was inevitably on the scoresheet as Liverpool took full advantage of the inactivity of their top-four rivals to thrash West Ham United 4-1 at Anfield and provisionally move into second in the Premier League.
Leicester City's Premier League title defence got off to a terrible start as they were beaten 2-1 at promoted Hull City, who shrugged off an injury crisis to shock the champions on the opening day of the new season on Saturday
Following is a match by match look at the English Premier League's weekend fixtures:
Manchester City set a new top-flight record of 15 consecutive wins as their seemingly unstoppable march towards the English Premier League title continued with a 4-0 romp at bottom club Swansea City.
"After feeling strange in the second half of the Burton game in September, I underwent a series of tests," he said.
In Pep Guardiola's 100th match in charge of the Manchester club, captain De Bruyne led from the front as City outclassed the Gunners, who have now suffered six home games without a win. Images from the EPL matches played on Sunday.
Not many people talk badly of Pep Guardiola, a sainted figure in football, but Manchester City's manager will find two of his most vocal critics facing him down at Old Trafford on Saturday.
In the 69th minute, the Argentine slid in to meet a cross from Sterling and, although it appeared Mings got the final touch for an own goal -- ultimately, a decision for the dubious goals committee -- no-one was going to persuade Aguero that he was not responsible for putting City two up.
Salah was seen training with a protective cast on his forearm this week but Klopp dismissed any fresh injury concern relating to the Egyptian.
Manchester City moved back into third place and almost guaranteed Champions League qualification thanks to a 3-1 home victory against West Bromwich Albion on Tuesday at the Etihad Stadium.
Chelsea coach Antonio Conte declared himself 'a serial winner' after leading his side to a 1-0 victory over Manchester United in the FA Cup final on Saturday and said it was up to the club to decide whether to fire him.
Manchester City claimed the win required to finally end Liverpool's relentless attempt to dethrone them as Premier League champions as they hit back from a goal down to crush Brighton and Hove Albion on the south coast on Sunday.
Two big derbies and an eventful weekend of football awaits us all...
News of all that's transpired on and off the football field
Pep Guardiola says Manchester City are not yet ready to compete with Europe's elite but his side will be confident of opening their Champions League campaign with victory over Borussia Moenchengladbach on Tuesday.
Images from the UEFA Champions League matches played across Europe on Wednesday