Sania Mirza, seeded ninth, advanced with a 6-1, 0-6, 6-1 victory over Finland's Emma Laine.
The third seeded Indian ace got the better of unseeded American Abigail Spears in her opening match of the WTA tournament.
Indian tennis ace Sania Mirza fought through a gruelling schedule to enter the last 16 of women's doubles and quarterfinals of mixed doubles by winning both her respective second-round matches on an all-win day for Indians in the US Open in New York.
Sania Mirza won her first title of the season and 23rd of her career when she and Bethanie Mattek-Sands shocked top-seeded Americans Abigail Spears and Raquel Kops-Jones in the summit clash of the Apia International in Sydney on Friday.