Both Mumbai and RCB, who are on 14 points from 11 games, will look to win the match and seal their spot in the play-offs and avoid some late dramas.
The first leg match between the two teams this year finished in a tie before RCB clinched victory in the Super Over.
Check out the playing XIs of the two teams:
Mumbai Indians: Kieron Pollard (captain), Ishan Kishan, Quinton de Kock (w/k), Suryakumar Yadav, Saurabh Tiwary, Hardik Pandya, Krunal Pandya, James Pattinson, Rahul Chahar, Trent Boult, Jasprit Bumrah.
Royal Challengers Bangalore: Virat Kohli (captain), Devdutt Padikkal, Josh Philippe (w/k), AB de Villiers, Gurkeerat Singh Mann, Shivam Dube, Chris Morris, Washington Sundar, Dale Steyn, Mohammed Siraj, Yuzvendra Chahal.