Leander Paes and Lukas Dlouhy fell for the third consecutive time in a month to Canada's Daniel Nestor and Nenad Zimonjic of Serbia as they were knocked out of the Cincinnati Masters on Friday.
The Indo-Czech pair were defeated 6-7 (6), 6-7 (5) by second seeds Nestor and Zimonjic in the quarter-finals of the hard-court tournament.
Nestor-Zimonjic had eliminated Paes and Dlouhy in the semi-final of Wimbledon and the Rogers Cup in Toronto.
The duo had gone on to win both the tournaments.
They will take on the Israeli pair of Andy Ram and Jonathan Erlich in the semi-finals in Cincinnati.
Mahesh Bhupathi and Bahaman partner Mark Knowles will contest the other semi-final with top seeds Mike and Bob Bryan of the USA.