US Open champion Samantha Stosur lost in the second round of the China Open on Tuesday, beaten for the second time in a week by Russian Maria Kirilenko.
Australian Stosur, the sixth seed and World No.7, was beaten 7-5, 1-6, 7-5 by Kirilenko, who defeated her at the same stage of last week's Pan Pacific Open in Tokyo.
"I didn't get off to as good a start as you want going into a third set," said Stosur. "Three love down and then 5-2 down - that's not a deficit you want to be in when it's the last set of the match.
"I've only played two tournaments since winning the US Open, so I don't think it's the end of the world with the two results that I've had," she added.
Defending champion Caroline Wozniacki reached the Beijing third round with a text-book 6-2, 6-3 win over Australian Jarmila Gajdosova.
The Danish World No.3, who had struggled in her first round, was rarely troubled by the big-hitting, 34th-ranked Gajdosova.
She will now meet Kaia Kanepi of Estonia, who beat her in the third round in Tokyo last week.
Men's first seed Jo-Wilfried Tsonga smashed his way to the second round, beating Bulgarian Grigor Dimitrov 7-6, 7-5.
The 70th-ranked Dimitrov made Frenchmen Tsonga work hard, forcing a tie-break in the first set, but the world number seven broke serve twice from four opportunities and sealed the match with an overhead smash to signal his title intentions.
"Of course I think I have chance, but it's tough for me to say how much," said Tsonga.
Spain's Marcel Granollers beat fifth-seeded Frenchmen Gilles Simon 6-3, 6-1 while Czech Tomas Berdych, seeded third, defeated Austrian Jurgen Melzer 7-5, 7-5.
The showcase WTA women's and ATP men's tournament at the National Tennis Centre in the Chinese capital have suffered a bout of shock exits and injury pull outs.
Home favourite and World No.6 Li Na exited in the first round while World No.2 Maria Sharapova pulled out with injury.
Men's World No.1and defending champion Novak Djokovic also withdrew with a back complaint.