The Stamford Bridge clash (2130 IST) is one half of a heavyweight Sunday double bill as Manchester United also visit Manchester City (1900 IST).
Ole Gunnar Solskjaer believes the club's old guard will face real competition after manager Alex Ferguson's spending spree.
IMAGES from the English Premier League matches played on Sunday.
Everton's Romelu Lukaku spared his side a fifth straight defeat by snatching an added-time equaliser to salvage a 1-1 home draw with West Ham United in the FA Cup third round on Tuesday.
Steven Gerrard scored twice as Liverpool beat West Ham United 3-0 at Upton Park on Saturday to move back on top of the Premier League and keep the pressure on Manchester United in the title race.
Jose Mourinho was purring like a cat that had devoured the leftovers from Christmas dinner but it did not stop him showing his professional claws after his Chelsea side eased past West Ham United 2-0 on Friday.
West Ham United manager Gianfranco Zola has pledged his long-term future to the club by signing a new contract until 2013.
Arsenal ended their away hoodoo against Premier League title challengers with a 2-0 victory at Manchester City on Sunday that left Chelsea five points clear at the top.
An English FA arbitration panel has ruled in favour of Sheffield United's claim for compensation against West Ham United in the Carlos Tevez affair, the Championship (second division) club confirmed on Tuesday.
Images from the English Premier League matches played on Wednesday night.
Gianfranco Zola, one of the greatest overseas players to grace the English game during his seven years at Chelsea, was named as the new manager of their Premier League rivals West Ham United on Thursday.
Southampton's Ronald Koeman has been named Premier League manager of the month for January, becoming the first Saints manager to receive the award on three separate occasions, while Manchester City striker Sergio Aguero won the players' award.
Chelsea have condemned online racist abuse aimed at defender Reece James and called on social media platforms to take tougher action against users who engage in such 'despicable behaviour'.
Liverpool opened up a seven-point gap at the top of the English Premier League with a 1-0 win at Brighton & Hove Albion on Saturday, while Arsenal's poor away form continued with a 1-0 defeat at West Ham United.
Former Chelsea and England midfielder Frank Lampard announced his retirement from professional soccer on Thursday after spending last year with New York City in Major League Soccer in the United States.
Manchester City's stellar season gathered yet more momentum as the runaway English Premier League leaders reached the League Cup semi-finals with a penalty shootout victory at Leicester City.
Schar's goal for Newcastle United in the 1-1 draw with Watford should have been chalked off
Manchester United crushed Derby County 4-1 away while Everton beat Aston Villa 3-1 at Goodison Park on Sunday to reach the quarter-finals of the FA Cup. United were pushed all the way by the Championship (second division) strugglers in the League Cup semi-finals last month but cruised home this time with goals by Nani, Darron Gibson, Cristiano Ronaldo and Danny Welbeck.
Ryan Giggs scored a sublime goal to seal a 1-0 win for Manchester United at West Ham United on Sunday that sent them back to the top of the Premier League.
Rafa Benitez's risky decision to start Fernando Torres and Dirk Kuyt on the bench looked like a masterstroke on Saturday after the strikers came on late to earn a 3-2 victory at Portsmouth which sent Liverpool top. Liverpool's grandstand finish moved them one point clear of Premier League champions Manchester United, at least until Sunday when Alex Ferguson's side visit West Ham United for one of their two games in hand.
Craig Bellamy scored his second goal since joining Manchester City to earn his side a 1-0 victory over Middlesbrough in the Premier League on Saturday.
Responding to an initiative already run by fans of both clubs, City and United will donate 50,000 pounds each to the Trussell Trust, a support network of more than 1,200 food banks.
Having headed into the match tied on 47 league goals with West Ham's former stalwart Paolo Di Canio, Antonio was delighted to have surpassed the Italian as he celebrated by lifting a cardboard cut-out of himself at the side of the pitch.
West Ham United avoided the fate of Premier League rivals Stoke City when they knocked League One (division three) giantkillers Hartlepool United out of the FA Cup 2-0 on Saturday.
Wales forward Craig Bellamy completed his transfer from West Ham United to Manchester City on Monday after the London club turned down an offer from Tottenham Hotspur.
High drama ensued during the English Premier League matches on Wednesday as Spurs manager Jose Mourinho was booked while Brighton stunned Chelsea via Alireza Jahanbakhsh's superb equaliser to deny the Blues victory. Here is all the EPL action in IMAGES from Wednesday's matches.
Chelsea brushed aside London rivals West Ham United with a 2-1 away win that restored their 10-point lead at the top of the Premier League on Monday.
Aston Villa took full advantage of the absence of the other Premier League high-fliers on Saturday, winning 1-0 at West Ham United to climb to third. A deflected James Milner shot 12 minutes from time gave Villa 34 points from 18 games and pushed them above Manchester United (32).
Chelsea missed the chance to reclaim top spot in the Premier League when they were held to a 1-1 home draw by West Ham United on Sunday, a day after Liverpool, Manchester United and Arsenal also drew.
Premier League leaders Liverpool stumbled again at home on Saturday, needing two Steven Gerrard goals to salvage a point in a 2-2 draw with Hull City.
Liverpool went top of the Premier League on Monday after a goalless home draw with West Ham United.
Pat Lampard, mother of Chelsea midfielder Frank and wife of former West Ham United player Frank Senior died on Thursday, Chelsea said in a statement.
Images from Sunday's English Premier League matches.
Argentine striker Carlos Tevez will make his Manchester United debut on Wednesday.
Chelsea's long unbeaten home record in the Premier League ended on Sunday when Liverpool earned a 1-0 victory to take over at the top of the standings. Xabi Alonso's deflected first-half shot sealed the points for the visitors, who move three points clear of Chelsea with 23 points from nine games. It was Chelsea's first home reverse in the league since February 2004, a run of 86 unbeaten matches.
Manchester United midfielder Bastian Schweinsteiger has been charged with violent conduct by the Football Association (FA) after clashing with West Ham United's Winston Reid.
The world governing body FIFA has referred the proposed transfer of Carlos Tevez from West Ham United to Manchester United to the Lausanne-based Court of Arbitration for Sport (CAS).
Hull City gatecrashed the Premier League's top four again on Sunday with a 1-0 home defeat of West Ham United.
Chelsea midfielder Frank Lampard and defender Branislav Ivanovic will be out of action until the end of January, the Chelsea website reported on Wednesday.
Argentina midfielder Javier Mascherano signed a four-year contract with Liverpool on Friday.