Liverpool had won each of their previous four home leagues games in which they conceded first and 12 minutes later they had turned another match on its head as Roberto Firmino's trickery set up Mane to give the hosts the lead at the second attempt.
Arsenal launched their bid for a first Premier League crown in five years with a comfortable 1-0 win over promoted West Bromwich Albion on the opening day of the season on Saturday. Liverpool, who have their eyes on a first title since 1990, also got off to a winning start by beating Sunderland 1-0 at the Stadium of Light with a late goal from Fernando Torres.
Arsenal will host Newcastle United in the outstanding League Cup third-round tie after the draw was made on Saturday.
Former England midfielder Paul Gascoigne is being held under the Mental Health Act, a police source said on Thursday.
Liverpool boss Juergen Klopp has beaten Manchester United only twice in his career and never at Old Trafford -- his worst record against any Premier League side.
Newcastle United midfielder Joey Barton was released from jail on Monday after serving 2-1/2 months of a six-month sentence for attacking a teenager last year.
Michael Owen scored Newcastle United's first goal since the return of Kevin Keegan as manager on Sunday but they could still only draw 1-1 at home with north-east rivals Middlesbrough.
Arsenal beat Newcastle United 3-0 to edge ahead of Manchester United in the English Premier League.
News of all that's transpired on and off the football field
Manchester City's hopes of remaining in the Premier League title race will hinge on how the defending champions negotiate the next five days with matches against Everton and Chelsea, midfielder Bernardo Silva has said.
The midfielder was granted bail but with strict conditions and ordered to reappear in court on January 16.
Liverpool manager Brendan Rodgers stressed that his team would give everything to qualify for the Champions League after a 2-0 victory over Newcastle United on Monday left them four points behind Manchester City in the Premier League.
Liverpool manager Brendan Rodgers stressed that his team would give everything to qualify for the Champions League after a 2-0 victory over Newcastle United on Monday left them four points behind Manchester City in the Premier League.
Liverpool kept alive their hopes of Champions League football next season with a comfortable 2-0 Premier League victory on Monday against a Newcastle United side who finished with 10 men.
Newcastle United midfielder Joey Barton was refused bail and remanded in custody after he appeared at Liverpool Magistrates Court on Friday charged with common assault and affray.
Robin van Persie will play no part in Manchester United's busy holiday programme after being ruled out for a month with a thigh injury, manager David Moyes said on Friday.
Newcastle United defender Stephen Taylor equalised on the hour to earn a 1-1 draw against Arsenal at home.
Late goals from William Gallas and Tomas Rosicky gave Premier League leaders Arsenal a 2-0 win over Wigan Athletic on Saturday as champions Manchester United slipped to a 1-0 defeat at Bolton Wanderers. In another match, Steven Gerrard inspired fifth-placed Liverpool to a 3-0 victory at Newcastle United.
The race for the English title could finish next Sunday with the top two teams level on points for only the sixth time.
Chelsea beat Newcastle United 2-0 on Monday to go level on points with EPL leaders Manchester United.
Everton missed the chance to confirm a place in next season's UEFA Cup when they were beaten 1-0 by Arsenal in the Premier League on Sunday. Liverpool, knocked out of the Champions League by Chelsea on Wednesday, won their final home Premier League game, Fernando Torres notching his 32nd goal of the season in all competitions to earn a 1-0 victory over Manchester City.
Everton missed the chance to secure a place in next season's UEFA Cup when they were beaten 1-0 by Arsenal in the Premier League on Sunday.
Manchester United took a huge step towards retaining their Premier League title when they beat West Ham United 4-1 at Old Trafford on Saturday after playing more than half the match with 10 men.
Aston Villa thrashed local rivals Birmingham City 5-1 to take their goal tally to 15 in their last three EPL games.
Sunderland are still not safe after losing 2-0 at Newcastle United in the day's second derby, Michael Owen scoring twice for Kevin Keegan's resurgent side at St James' Park.
Holders Manchester City began their assault on the FA Cup with a 4-1 victory over fourth-tier Port Vale but Manchester United and Wolverhampton Wanderers face an unwanted replay after drawing 0-0 at Molineux on Saturday. Goals from Oleksandr Zinchenko, Sergio Aguero, Taylor Harwood-Bellis and Phil Foden made it a routine day for City, although Tom Pope had equalised for a Vale side sitting 74 places lower in the standings.
Tottenham Hotspur's poor start to the season showed little sign of improving when they were beaten 3-1 by Newcastle United.
Former Manchester United manager Alex Ferguson said he was worried about the impact manager Juergen Klopp was having at his old team's great rivals Liverpool.
The England striker had a second knee operation and will start an intensive rehabilitation programme immediately.
Speaking at a news conference in Newcastle, his club manager Sam Allardyce said the striker had suffered a torn thigh muscle and also had a suspected weakness in his stomach area which may require surgery.
Fernando Torres scored a hat-trick to inspire Liverpool to a 4-2 victory at Reading in the League Cup third round.
Leicester City has a chance to go top of the English Premier League table with a maximum nine points.
A stunning volley from Kenny Miller on his debut gave Derby County their first Premier League win of the season as they defeated previously unbeaten Newcastle United 1-0 at Pride Park on Monday.
Manchester City will be without David Silva, Raheem Sterling and captain Vincent Kompany for this weekend's visit to Chelsea, manager Manuel Pellegrini told reporters on Friday.
Lee Bowyer will serve a three-match ban after his claim for wrongful dismissal against Liverpool was rejected
Liverpool face Spurs in the game of the weekend, a day after title rivals Manchester City travel to struggling Fulham.
Images from the English Premier League matches played on Tuesday
Aston Villa moved into fifth place in the Premier League after a John Carew hat-trick sealed a 4-1 hammering of Newcastle United.
Everton tightened their grip on fourth place in the Premier League and the prospect of Champions League football with a 1-0 win over Reading on Saturday.
Former Newcastle United striker Alan Shearer said he had turned down an offer of a coaching role at the struggling Premier League club.
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