His overall record of five wins, two draws and seven defeats included shock losses to Hapoel Beer Sheva and Sparta Prague in the Europa League and at home to Cagliari in Serie A.
Media reports said former England manager Roy Hodgson was in line to replace De Boer at Selhurst Park.
A summary of Friday's action in the FIFA World Cup 2026 UEFA Qualifiers.
Arne Slot is the first to win the top flight in England where many of his compatriots have suffered dents to their reputations over the years.
Inter Milan have appointed former Ajax Amsterdam manager Frank de Boer as their new head coach on a three-year contract replacing Roberto Mancini.
Missing out on the last Euros in France and then the 2018 World Cup in Russia were a major setback and re-establishing their reputation as a footballing force is top priority for coach Frank de Boer and his team.
Midfielder Donny van de Beek has had to pull out of the Netherlands squad for the European Championship because of injury.
The identity of the Netherlands goalkeeper for their opening World Cup match remains a closely guarded secret
Frank de Boer ruled out accepting the Tottenham Hotspur job again on Friday, saying he was satisfied with his post at Ajax Amsterdam.
With the club football season over, and the World Cup only a couple of weeks away, rediff.com takes stock of how some of the top coaches in European football performed in their first season in charge.
The 71-year-old, who has battled with cancer over the last year, concluded his third spell as the Netherlands coach with their penalty shootout loss and will be replaced by Ronald Koeman.
De Jong is proud to join the likes of compatriots Ronald Koeman, Frank de Boer and Patrick Kluivert in heading to the Nou Camp, having dreamed of wearing Barca colours.
Goals from Freddie Hinds, Bobby Reid and Niclas Eliasson put the visitors through to the third round. Watford finished with 10 men after Jose Holebas was sent off.
The Dutch captain, 34, has won a Dutch record of 112 caps and had said he would retire after the tournament.
The veteran defender is set to make his 111th appearance for the Netherlands on Wednesday.
It will also come in front of 5,000 spectators who are being allowed into Saturday's game at the Amsterdam Arena.
Ajax Amsterdam scored after 72 seconds and added a second goal near the end to inflict a 2-0 home defeat on champions PSV Eindhoven and take over the lead of the Dutch league.
The Dutch were 2-0 up with 15 minutes left in the Euro 2020 match, only to allow their opponents two quick goals and the chance to share the points before Dumfries headed home a dramatic winner to the delight of the home fans.
Louis van Gaal has said he would consider joining Tottenham Hotspur once his contract with the Dutch national team finishes after this year's World Cup in Brazil.
More clubs should follow the Ajax Amsterdam model of promoting former players to executive roles, according to the Dutch side's assistant manager Dennis Bergkamp.
Holders France got their World Cup qualifying campaign off to a disappointing start with a 1-1 draw at home to Ukraine
The Euro 2020 Championship is being held across Europe for the first time in the competition's 60-year history, with 11 host cities in total.
Spurs striker Bergwijn is major casualty as Netherlands trim squad
Veteran Francesco Totti scored a stoppage-time winner from a penalty in his first appearance of the season as Roma beat Sampdoria 3-2 in Serie A on Sunday. The 39-year-old former Italy international has now scored in 23 consecutive league seasons for Roma. Sunday's goal lifted the team to within two points of early leaders Juventus, who defeated Sassuolo 3-1 on Saturday.
Mauricio Pinilla converted a late penalty to give Atalanta a 2-1 win over Inter Milan and condemn their troubled opponents to a third successive Serie A defeat on Sunday.
Miralem Pjanic's free kick gave Juventus a 2-1 win at Chievo on Sunday as goalkeeper Gianluigi Buffon celebrated his 600th Serie A appearance.
Juventus coach Massimiliano Allegri criticised his players for letting their guard down and losing 2-1 at arch-rivals Inter Milan after taking the lead in the second half at the San Siro.
Four-time European champions Ajax Amsterdam find themselves among the pre-qualifiers for the Champions League this year as Dutch football pays the price for its declining record in continental competition.
A summary of sports events and sports persons, who made news on Wednesday
Bayern Munich will be without experienced Franck Ribery when they meet Manchester City in their Champions League Group E opener on Wednesday with fellow winger Arjen Robben also doubtful, coach Pep Guardiola said.
Images from the World Cup qualifying matches played on Monday.
A makeshift England side beat Romania 1-0 in their final Euro 2020 warm-up game, while Belgium's Romelu Lukaku underlined his status as one of the world's top strikers with his 60th international goal to secure a 1-0 win over Croatia.
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Barcelona's preparations for next season were thrown off course on Friday when the Spanish champions unexpectedly announced coach Tito Vilanova was stepping down due to ill health.
Champions Juventus returned to the top of Serie A with a 4-0 home rout of Cagliari on Wednesday, while former leaders Napoli dropped to second after being held to a goalless draw at Genoa.
Following is a match by match look at the English Premier League's weekend fixtures:
Images from the English Premier League matches played on Sunday
Following is a match by match look at the English Premier League's weekend fixtures:
There may be little glamour in being a mid-table Premier League team but this season suggests that those clubs who become bored with such an existence can find the alternative is far worse.
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