Since winning 2-1 at home to Wolfsburg in September, United have scored only twice in three Champions League games. In the Premier League the record is five goals in the last six games.
The European champions are likely to play CSKA Sofia in the Champions League third qualifying round.
The world players' union has criticised European soccer's governing body UEFA for failing to enforce its own guidelines on racism following the abuse hurled at ManchesterCity's Yaya Toure in Moscow.
Barcelona must to wait to confirm a place in the Champions League last 16 after dropping points for the first time in Group D in an absorbing 0-0 draw at Olympiakos Piraeus on Tuesday.
Manchester United ended their one-year Champions League hiatus in emphatic style when Wayne Rooney struck a hat-trick in a 4-0 destruction of Club Bruges that sent the three-times winners through 7-1 on aggregate on Wednesday.
On a night of close finishes in all five first-leg playoff games, the 21-year-old Dutch winger opened his United account with a memorable performance in the famous number seven shirt previously worn by George Best, Eric Cantona and David Beckham.
The Chilean striker scored the winner in their UEFA Cup semi-final first leg against AZ Alkmaar.
It compounded a woeful few months for the club as coach Julen Lopetegui came and went before former player Santiago Solari replaced him in November. They sat sixth in La Liga and appeared a team in decline, sorely missing forward Cristiano Ronaldo, who left for Juventus last summer.
Late Griezmann strike ends Atletico's away day hoodoo
The Russian Football Union's anti-discrimination inspector has said the World Cup is a chance for Russia to show how open it is.
Photos from the Champions League matches played across Europe on Tuesday
Pep Guardiola will return to the Nou Camp in the Champions League group stage after his new club Manchester City were drawn against his former Barcelona team on Thursday. The two sides were drawn in Group C alongside Borussia Moenchengladbach and former European champions Celtic in one of the toughest of the eight sections. Spanish coach Guardiola, who won the Champions League twice with Barca, faced the Catalans when he was in charge of Bayern Munich two seasons ago and suffered a 5-3 defeat in the semi-finals.
The Russian Football Union (RFU) said on Tuesday it had ended its contract with national team coach Fabio Capello, three years before the country hosts the 2018 World Cup finals.
Images from the UEFA Champions League matches played on Tuesday night.
News of all that's transpired on and off the football field
Kazakhstan's Astana fought back to beat a youthful Manchester United side 2-1 at home, Arsenal's woes continued as Frankfurt's Daichi Kamada scored twice to secure a 2-1 win.
Last season's runners-up Liverpool, big-spending French league champions Paris St Germain and Carlo Ancelotti's Napoli were thrown together in the pick of the groups while holders Real Madrid must face last season's semi-finalists AS Roma.
Arsenal manager Arsene Wenger is to stand down at the end of the season after a reign of almost 22 years that made him the most successful boss in the Premier League club's history.
Images from Tuesday night's UEFA Champions League group stage matches.
Here are five talking points from the weekend's action:
VfL Wolfsburg reached the Champions League last 16 and dealt a knockout blow to Manchester United with a 3-2 victory to claim top spot in Group B and condemn their opponents to the Europa League on Tuesday.
A summary of all the Champions League matches played across Europe on Tuesday
Tottenham Hotspur claimed a first victory at Chelsea for 28 years with Dele Alli scoring twice in the second half as they came back to win 3-1 and cement fourth place in the Premier League on Sunday.
Victory for the Netherlands in Friday's Euro 2016 qualifier in Latvia would have been seen as practically guaranteed after a successful World Cup in Brazil but a faltering qualifying campaign has precipitated a confidence crisis.
IMAGES from the Europa League matches played on Thursday
German champions Bayern Munich have completed the transfer of former World Cup winner Xabi Alonso from Real Madrid on a two-year deal as they seek to boost their midfield options following a string of injuries.
Ruthless Bayern Munich scored five goals in the first 35 minutes on the way to a 7-1 demolition of AS Roma on Tuesday which bore an uncanny resemblance to Germany's win over Brazil by the same score in the World Cup semi-final.
All you must know about soccer's return to action after coronavirus
It is a mark of how far Tottenham Hotspur have come that they start as favourites to win what could be a pivotal Champions League Group E fixture away to Bayer Leverkusen on Tuesday despite the absence of key defender Toby Alderweireld.
Manchester United's insistence on playing possession football under manager Louis van Gaal means they take far more passes for every shot than any other Premier League team, statistics released on Monday showed.
Cristiano Ronaldo set a record for goals scored in the group stage of the Champions League of 11 when he netted four against Malmo in Group A on Tuesday.
Manchester United found a home grown solution to their goalscoring problems in the shape of Jesse Lingard as the 22-year-old celebrated his first Premier League start by breaking an Old Trafford stalemate on Saturday.
A summary of Wednesday's group matches in the UEFA Champions League.
Barcelona forward Lionel Messi equalled the Champions League scoring record of 71 goals when he struck for the second time in the 76th minute of Wednesday's Group F match at Ajax Amsterdam.
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