The Real Madrid midfielder has ruled himself out of the match because of an ankle injury.
Local media reported the team captain, a dressing-room heavyweight and a huge fan favourite, would earn 10 million euros a season after tax, making him one of the best-paid members of Real's expensively assembled squad
The Real Madrid striker pulled up in training because of pain in his left thigh.
Champions Barcelona moved five points clear at the top of La Liga with a 2-1 win at Getafe, while Real Madrid fell to a 2-0 defeat by Real Sociedad.
Real Madrid's centenary year celebrations ended on a high note when the team fought back from 3-0 down to draw 3-3 against a World Selection.
Here, Reuters Sport highlights five reasons why last season's double winners have collapsed.
Real Madrid scrambled through to the final of the King's Cup with a 2-1 aggregate victory over Sevilla.
A summary of sports stories from across the globe
Real Madrid beat Valencia 3-0 on Wednesday in a King's Cup quarter-final first leg victory.
Manchester United has reportedly been linked with a move for Welsh forward Gareth Bale in recent weeks as Real Madrid has revealed that they are willing to sell the former Tottenham Hotspur star.
The England captain aggravated the injury in Real Madrid's 1-0 Champions League win over Racing Santander.
The nine-times European Cup winners beat Partizan Belgrade and stayed on top of their group in the Champions League.
Real fought back after a calamitous own goal from keeper Keylor Navas gave Betis the lead in the 25th minute, just after the Costa Rican escaped a possible red card. Cristiano Ronaldo pulled the hosts level in the 41st with a diving header.
Real Madrid trimmed Barcelona's lead at the top of La Liga to one point when they recovered from conceding an early goal to secure a stirring 3-1 comeback win in the 'Clasico' on Saturday.
'There is no advantage. I always prefer to play in front of supporters even away from home because that's what football is all about, but that's the situation we face'
Hegerberg hat-trick fires Lyon to fourth straight Champions League
'Cristiano scored 50 goals and you can't find someone today who scores that many. Some of us have to take a step forward and, while not scoring 50, what we need is two or three players who score 15, 20, or 10 goals and we don't have that.'
Get set to be amazed as Rediff.com has all that and more sporting action from the past week encapsulated in this super photo feature.
Holders Real Madrid breezed into the last 16 of the Champions League with two games to spare when a Karim Benzema strike secured a 1-0 win in their Group B match at home to a toothless Liverpool on Tuesday.
"My motto is never to make promises, but instead deliver the goods," said Real Madrid's new Portuguese coach.
Cristiano Ronaldo has urged Real Madrid to renew his contract and said he wanted to see out his career in the Spanish capital. Ronaldo's immediate future at Real has been in doubt all season, with speculation growing throughout the year that he was plotting a move to Paris Saint-Germain but the prolific Portuguese has now made it clear he wants to stay at the club. "Real Madrid would be making a smart decision if they offered me a new contract," Ronaldo told Spanish television programme La Sexta on Wednesday. "I want to stay here, there have been good moments and bad moments. Four years ago I wasn't happy here but now I am and I can't think of a better club to be at than Real Madrid, there's no team like it. The other clubs can forget it." Ronaldo overtook Raul Gonzalez as Real's all-time top scorer earlier this season and on Saturday will be hoping to inspire the team to their 11th European Cup success when they take on Atletico Madrid in the Champions League final in Milan.
Real went top with one game to play after thrashing Atletico Madrid 4-0 while rivals Sociedad slipped to a 3-2 defeat at Celta Vigo.
Real Mallorca rallied from a goal down at half-time to beat the European champs 5-1 in the Spanish League.
The 1-1 draw put Real four points clear at the top of the table.\n\n
Real Madrid have moved to broaden their options in attack by agreeing to sign Mexico striker Javier Hernandez on loan from Manchester United for the 2014-15 season.
The former Spain coach said restoring a winning mentality in the club's players would be his main priority.
Marco Asensio followed up his brilliant late goal in Sunday's first leg with a stunning effort from 30 metres in the fourth minute that proved a punishing blow for the Catalans.
Lionel Messi hit a hat-trick as Barcelona warmed up for the El Clasico with Real Madrid next weekend with a 7-0 victory over Osasuna that put them four points off the top of La Liga.
Real Madrid's early-season woes deepened when they lost 2-1 at home to La Liga champions Atletico Madrid, while substitute Neymar struck twice in Barcelona's 2-0 win against visiting Athletic Bilbao on Saturday.
The World and European champions close out their centenary celebrations with a match against a FIFA World Selection, featuring many of the best players on the planet, on Wednesday.
