Welsh world and Olympic champion Geraint Thomas, Isle of Man rider Peter Kennaugh and the England pair of Ben Swift and Ian Stannard, said they were opting out of the Games as they feared for their health after reading reports about the dengue outbreak and the "filthy" conditions at the Games Village.
Chris Froome was reminded just how quickly the Tour de France title could slip from his grip as his Sky team mate Geraint Thomas suffered a freak crash in Monday's 16th stage.
Chris Froome moved closer to a maiden Tour de France title with an awe-inspiring victory on top of the intimidating Mont Ventoux, pulling away from his rivals in brutal fashion seven kilometres from the finish on Sunday.