Chief Minister M K Stalin inspected several inundated areas here along with top officials including Chief Secretary V Irai Anbu and directed authorities to take swift action to drain flood water.
The ministry said 151 out of the 578 people who contracted the infection have recovered or migrated.
Tamil Nadu, Telangana and West Bengal reported their first COVID-19 variant Omicron cases on Wednesday, four more persons each tested positive in Maharashtra and Kerala.
Stating that the fight against COVID-19 is at the final stage, Union Health Minister Mansukh Mandaviya on Thursday cautioned against letting the guard down before it is completely over and requested states to enhance the vaccination coverage and motivate the over 12 crore beneficiaries who are due for their second dose to take it.
People must also avoid mass gatherings, and new year celebrations need to be at low intensity, the government said.
Tamil Nadu Chief Minister M K Stalin's Cabinet, including him, would be 34-member strong and he has retained senior leaders like Duraimurugan and over a dozen shall be ministers for the first time.
The Tamil Nadu assembly on Tuesday once again adopted the anti-NEET Bill, returned days ago to the government by Governor RN Ravi, with the ruling Dravida Munentra Kazhagam and principal opposition All India Anna DK reaffirming their opposition to the test.
Most of those who tested positive either recently arrived from African countries or were in contact with such people.
Governor Banwarilal Purohit administered the oath of office and secrecy to 68-year old Stalin, for whom this would be the first stint as CM
Protests were held across Tamil Nadu with raising of slogans-- "Vendum Vendum Kudineer Vendum" (we want water) and "Edappadi Arasai Kandikirom" (we condemn chief minister Edappadi K Palaniswamy's government).