Thomas Meunier volleyed a spectacular last-minute goal to give Paris St Germain a 2-1 win at FC Basel, which took them into the last 16 of the Champions League on Tuesday.
The three teams with 100 percent records in this season's Champions League can secure their places in the knockout stage this week with two games to spare.
Real Madrid coach Carlo Ancelotti is counting on his wealth of experience to help fix the holders' midfield woes as they prepare to host FC Basel in Tuesday's Champions League Group B opener at the Bernabeu.
Pep Guardiola says Manchester City are not yet ready to compete with Europe's elite but his side will be confident of opening their Champions League campaign with victory over Borussia Moenchengladbach on Tuesday.
Manager Brendan Rodgers has ended whatever honeymoon period new striker Mario Balotelli was enjoying at Anfield, telling him he needs to start scoring goals after finding the net just once in seven appearances for Liverpool.
There will be plenty of tension in the air in North London on Wednesday when out-of-sorts Arsenal face Borussia Dortmund seeking to qualify from the Champions League group stage for the 15th successive season.
Real Madrid earned their first-ever win over Liverpool with a wondrous Cristiano Ronaldo goal spearheading a 3-0 Champions League victory at Anfield on Wednesday which appeared as classy as it was dominant.
Atletico Madrid sealed top spot in Champions League Group D after second half goals from Frenchmen Kevin Gameiro and Antoine Griezmann but Napoli were held to a 0-0 Champions League draw at home by Dynamo Kiev.
US Open champion Martin Kaymer sank an eight-foot birdie putt at the first extra hole to beat Bubba Watson in the four-man PGA Grand Slam of Golf in Bermuda on Wednesday.