He has not played since the last group game against Czech Republic when he picked up a groin injury.
Italy suffered a serious blow ahead of next month's World Cup when midfielder Riccardo Montolivo broke his leg during a warm-up game against Ireland at Craven Cottage on Saturday.
Italy midfielder Daniele De Rossi looks unlikely to face Germany in Saturday's Euro 2016 quarter-final because of a bruised thigh.
Brescia captain Daniele Gastaldello also expressed concern.
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