Ajax were joined by Young Boys, who stunned Dinamo Zagreb 2-1 away for a 3-2 aggregate win over the Croatians, and AEK Athens who scraped a 1-1 home draw with FC Vidi after a 2-1 win in the first leg in Hungary.
Carlos Bacca claimed the plaudits with a superb double strike, including a late winner to decide a pulsating clash that began at a hair-raising pace with four goals in the first half.
Sevilla stayed firmly on course for a second consecutive Europa League crown when an Aleix Vidal double and a Kevin Gameiro strike secured a thumping 3-0 win at home to Fiorentina in their semi-final first leg on Thursday.