India vice-captain Ajinkya Rahane, senior batsman Rohit Sharma and pacer Shardul Thakur arrived in Chennai on Tuesday for the first two Tests of the four-match series against England.
Rahane, Rohit and Thakur flew in from Mumbai and headed to the hotel where members of the two teams will be put up as part of the bio-bubble, the Indian squad's local liaison officer said.
The other Indian players, including skipper Virat Kohli, are expected to reach Chennai in batches on Wednesday.
While some England players like Ben Stokes, Jofra Archer and Moeen Ali are already in the city, the others will be arriving on Wednesday.
Skipper Joe Root will be among the players to reach Chennai from Sri Lanka, where England won the Test series 2-0 on Monday.
The players of the two teams will undergo six-day quarantine at Hotel Leela Palace in Chennai and will undergo COVID-19 testing before they are allowed to start practice, a Tamil Nadu Cricket Association official said.
"Members of the two teams will be put up at Hotel Leela Palace along with match officials. They will be under quarantine for six days and are likely to start practice from February 2," the official said.
The first Test will be played at the M A Chidambaram stadium from February 5 and the second match from February 13 at the same venue, with the remaining two Tests to be played in Ahmedabad.