Manchester United will be without Wayne Rooney and Paul Scholes for three games after the FA's Independent Disciplinary Commission rejected their claims on Tuesday of wrongful dismissal in a friendly against Porto.
A statement on the FA's website said their bans would start on August 23, meaning the pair are free to play in United's opening Premier League fixture against Fulham on Sunday.
Rooney was shown a straight red card after catching Pepe in the face with his arm while jumping for a high ball in the opening game of the Amsterdam pre-season tournament on August 4.
Scholes followed after a clumsy tackle in the second half. Both players scored in the 3-1 victory.
The FA's decision means Scholes and Rooney will miss the Premier League matches at Charlton Athletic and promoted Watford and at home to Tottenham Hotspur.
Manchester United made no comment.