Iniesta decided the game at Old Trafford, designed to prepare both sides for next month's Euro 2008 qualifiers, with a dipping shot from outside the area in the 63rd minute.

England huffed and puffed for much of the match, but carved out only one clearcut scoring chance which striker Peter Crouch missed towards the end of the first half.

The defeat marks another disappointment for England coach Steve McClaren, whose Euro qualifying campaign in Group E has been hit by a home draw with Macedonia and a defeat in Croatia.