Daley Blind's injury-time equaliser rescued a 1-1 draw for Manchester United against West Ham United on Sunday but a point was not enough to regain third spot in the Premier League.
Spanish newspapers said Real were already in negotiations with Newcastle United over the defender.
A preview of the English Premiership's first round of matches.
The victory lifted Newcastle up to 10th place in the Premier League. West Brom stay 17th.
Arsenal stayed top of the Premier League after two goals in five minutes from Spain international midfielder Santi Cazorla set them on their way to a 2-0 win over Fulham who remain mired deep in the relegation battle.
Under-fire Jose Mourinho had been on the verge of delivering the perfect response to his critics on Saturday with Manchester United closing in on a second consecutive comeback win, at the home of his old club Chelsea to boot.
Twelve months ago Liverpool were ripping up the record books on the way to their first English top-flight title for 30 years but defeat by Everton on Saturday left them mulling a host of far less flattering statistics.
Manchester United manager has been penalised for abusing a match official.
Chelsea manager Maurizio Sarri made a winning start to life in the Premier League as his team enjoyed a 3-0 win over Huddersfield Town at the John Smith's Stadium on Saturday.
Owen missed Newcastle United's goalless draw at Portsmouth at the weekend with a leg injury.
Images from the EPL matches played on Saturday
A round-up of Saturday's matches in the English Premier League.
Michael Owen scored his first Newcastle United goal to help them beat Blackburn Rovers 3-0.
Images from the English Premier League matches played on Saturday.
Former Manchester United striker Ole Gunnar Solskjaer is set to take over as manager at Premier League Cardiff City, Norwegian media reported on Wednesday.
England's Kieron Dyer says being named in media coverage of a London hotel sex incident knocked the "cockiness" out of him ahead of Euro 2004.
'We are upset because we have lost a great professional and a top-class player,' Real Madrid director of football Arrigo Sacchi said.
Winter returned to Anfield on Friday but while the temperature dropped, the standards of Juergen Klopp's side certainly did not as Sadio Mane and Mohamed Salah both struck twice in a 5-0 thrashing of relegated Huddersfield Town.
News of all that's transpired on and off the football field
Ivory Coast striker Didier Drogba handed Olympique Marseille a slender 1-0 lead over Inter Milan in quarter-final, first leg match.
Michael Owen's first-half double helped Liverpool crush Blackburn Rovers 4-0 and reclaim fourth place in the English premier league.
A review of the weekend action in the leading European leagues.
Manchester United midfielders Ander Herrera and Adnan Januzaj have returned to training ahead of the Premier League trip to Stoke City, manager Louis van Gaal said on Tuesday.
Last season's UEFA Cup semi-finalists marched into the last 32 with their third successive win in the group stage.
Manchester United will await tests on winger Angel Di Maria to see if he has a chance of facing Tottenham Hotspur on Sunday after the Argentine suffered a pelvic injury in training.
Premier League leaders Arsenal host north London rivals Tottenham Hotspur in the standout tie in the draw for the third round of the FA Cup made on Sunday.
A hat-trick by Paul Scholes was the feature of their 6-2 win in the English premiership.
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