Barcelona beat local rivals Espanyol 2-0 in the Catalan derby on Saturday to maintain their 10 point lead at the top of La Liga, while Real Madrid scraped a 3-2 win against bottom side Huesca on Sunday.
David Beckham returned from a six-week injury absence to set up Real Madrid's winner in a 2-1 victory over Primera Liga title rivals Valencia at the Bernabeu on Saturday.
Sevilla and Real Madrid kept the pressure on leaders Barcelona with home wins in the Primera Liga on Sunday.
The champions of Italy, England, France and Germany continued to dictate the pace in the major European leagues at the weekend.
Real Madrid's reliance on their talisman Cristiano Ronaldo was more evident than ever on Tuesday as the Spanish and European champions meekly lost 1-0 at Espanyol in La Liga.
Skipper Raul struck twice as Real Madrid got the better of old foes Bayern Munich with a 3-2 win at the Bernabeu in the first leg of their Champions League first knockout round tie on Tuesday.
Real Madrid and Bayern Munich are hoping a return to the European stage in their last 16 Champions League showdown.
News of all that transpired on and off the football field
Uruguayan midfielder Fabian Canobbio scored a contentious goal to give promoted Celta Vigo a 3-2 win.
La Liga leaders Barcelona moved 10 points clear with a 4-1 win at Real Betis on Sunday after second place Atletico Madrid slipped up at Athletic Bilbao on Saturday in a 2-0 defeat.
Chelsea will be hoping to emulate London rivals Arsenal by beating Barcelona in their Champions League first knockout round tie.
Real Madrid were dumped out of the King's Cup by Primera Liga strugglers Real Betis on the away goals rule after they were held to a 1-1 draw at the Bernabeu on Thursday.
The Dutch striker will join Real Madrid from Manchester United on a three-year contract, the Primera Liga club said.
Real Madrid have endured a miserable season since Zinedine Zidane left in May, first sacking Julen Lopetegui and then Santiago Solari.
Pepe has blasted the Liga club's fans as "unenthusiastic", contrasting the hushed atmosphere of the Santiago Bernabeu stadium with the cauldron of noise he is now exposed to with Turkish champions Besiktas.
Goals from Ronaldo and Roberto Carlos moved Real Madrid up to second in the Primera Liga on Sunday.
Saturday's game should give Barcelona's teenage Argentine Lionel Messi the chance to pit his skills against Real Madrid's Brazilian wizard Robinho.
Real Madrid paid homage to Cristiano Ronaldo as their outright leading scorer on Friday even though the official statistics show he has yet to overhaul former Spain striker Raul.
Espanyol put aside relegation worries to clinch a scintillating 4-1 win over favourites Real Zaragoza in the final.
Real Madrid and Barcelona pulled two points clear in La Liga when Cristiano Ronaldo set a club scoring record in Real's 3-0 stroll against Levante and Neymar hit four as Barca beat Rayo Vallecano 5-2 on Saturday.
Real Madrid failed to keep the pressure on leaders Barcelona as they were held to a draw by relegation-threatened Real Sociedad.
Real Madrid's Brazilian contingent overwhelmed Real Mallorca 4-0 to help move the team up to third in the Primera Liga.
Ronaldinho was in inspirational form as he returned to lead Barcelona to a 5-1 home victory over an unfortunate Real Betis in the Primera Liga on Saturday.
Ajax, four-times European Cup winners who are in the knockout stages for the first time in 13 years, have enhanced their reputation as a talent factory due to the rise of homegrown Dutch players Frenkie de Jong and Matthijs de Ligt.
A superb strike from Jose Luis Morales condemned Real Madrid to a 1-0 defeat away to Levante on Saturday which saw them unseated at the top of the La Liga standings by Barcelona. Real's problems deepened with a suspected ankle injury to Eden Hazard, who limped off the pitch four days before their Champions League showdown with Manchester City and a week before their showdown with Barca in the 'Clasico'. Real's problems deepened with a suspected ankle injury to Eden Hazard, who limped off the pitch four days before their Champions League showdown with Manchester City and a week before their showdown with Barca in the 'Clasico'.
Gareth Bale said Real Madrid are determined to wrest back the Spanish league title from Barcelona this season after going four years without tasting La Liga success. Bale has won the Champions League twice and the King's Cup since joining the Bernabeu club in 2013, but the league title has proved elusive. Real missed out on the league to Barcelona on the final day of last season by a point and have not won the title since 2012, when they collected a record 100 points under Jose Mourinho.
Zinedine Zidane cast doubt on his long-term future at Real Madrid by saying he is unsure if he will be in charge of the club next season. The former midfielder was named as Rafael Benitez's successor in January when he signed a contract until June 2018. But when asked what role he would have in the Liga club's transfer dealings for next season, Zidane said he did not know if he would still be at the Bernabeu. "I can't know what role I'm going to have if I don't know if I'm going to be here. We'll see what happens at the end of the season," Zidane was quoted as saying by Spanish newspaper Marca. The 43-year-old was also asked if Madrid would make another attempt to sign David de Gea after their move for the Manchester United and Spain goalkeeper fell through on the last day of the transfer window last August.
Real Madrid made it two wins in two La Liga outings this season when Karim Benzema's scuffed 10th-minute strike secured an uninspiring 1-0 win at Granada on Monday.
Brazilian ace Ronaldo returned from injury to give Real Madrid a 1-0 victory in the Primera Liga.
A 3-0 victory took Barcelona to the top of the Primera Liga.
Real Madrid have exonerated Argentina winger Angel Di Maria over an incident in Monday's La Liga game at home to Celta Vigo when he was caught on camera grabbing his crotch while being substituted.
Real Madrid coach Zinedine Zidane has opened the door to out-of-favour midfielder James Rodriguez leaving the club by admitting the player's lack of appearances could become a problem.
