An insatiable Lionel Messi scored for the eighth game in a row in all competitions as La Liga champions Barcelona saw off a gutsy Girona side 2-0 to go five points clear at the top of the standings.
Isco scored in the sixth minute of stoppage time as Spain launched an improbable fightback to snatch a 2-2 friendly draw against England with both their goals coming after the 89th minute at Wembley on Tuesday.
Liverpool substitute Adam Lallana struck deep into stoppage time to snatch a 5-4 win over shell-shocked Norwich City in an extraordinary Premier League game at Carrow Road on Saturday.
Wayne Rooney struck with a 74th-minute free kick to give England a 1-0 win over 10-man Estonia in a Euro 2016 Group E qualifier on Sunday and move to within six goals of Bobby Charlton's record tally of 49.
At least two of the eight first-round groups of four produced tough obstacles for their participants to progress to the knockout rounds.
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A round-up of all the international friendlies played on Tuesday
Holders Spain suffered their first defeat in qualifying for a major tournament in eight years when Miroslav Stoch nodded a late goal to earn Slovakia a shock 2-1 victory in Euro 2016 Group C on Thursday.