Later in the day, Commonwealth Games champion Lakshya Sen will face Chico Aura Dwi Wardoyo of Indonesia.
Malvika Bansod pulled off a sensational straight-game victory over Paris Olympics bronze medallist Gregoria Mariska Tanjong of Indonesia in the women's singles opening round.
Satwiksairaj and Ashwini showed top-notch fighting spirit before going down
The script remained the same in the second game as well, with Sindhu maintaining her firm grip over the proceedings to race to a 6-0 lead in just two minutes.
Commonwealth Games champion Parupalli Kashyap, Sameer Verma and the mixed doubles pair of Satwiksairaj Rankireddy and Ashwini Ponnappa notched thrilling victories to enter the quarter-finals of the India Open Super 500 World Tour badminton tournament in Delhi on Thursday.
The 26-year-old is now the lone Indian survivor in the BWF World Tour Super 750 tournament.
Satwik and Ashwini, who reached the semi-finals at Toyota Thailand Open Super 1000 in January, will meet the winner of the match between fifth-seeded Malaysians Tan Kian Meng and Lai Pei Jing and Germany's Jones Ralfy Jansen and Kilasu Ostermeyer.
Star shuttlers, including P V Sindhu, will chase individual gold medals but doubles would also under the spotlight as India would aim to retain the mixed team title and continue their consistent run at the Commonwealth Games.