Morne Morkel then removed Ricky Ponting for 62 when Australia's leading run-scorer tried to cut a short delivery outside off stump and edged it high to Jacques Rudolph at second slip.
Ponting resisted for more than three-and-a-half hours in a defiant innings that could prolong the embattled former skipper's career.
Mike Hussey and Brad Haddin put on 50 for the sixth wicket before Philander struck with the first ball of his second spell, two overs before the tea break.
The left-handed Hussey tried to play across the line of a delivery that straightened into the pads and was given out lbw for 39.
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