Mourinho's tinkerings meant a first start of the season for midfielder Scott McTominay, playing on the right of a three-man defence, while Anthony Martial played instead of the dropped Alexis Sanchez. On this evidence, more changes may be needed when United take on Valencia in the Champions League on Tuesday.
Both sides will be high on confidence with an aim to come out all guns blazing.
Goals rained in for Manchester City and Manchester United but Juergen Klopp's first game in charge of Liverpool was solid rather than spectacular with his new side drawing 0-0 at Tottenham Hotspur in the Premier League on Saturday.
Guardiola has crafted a sleek offensive unit but, after a breathless opening 15 minutes at The Emirates, they appeared to ease off as their intensity levels dropped and they allowed Arsenal back into the match.
Tough conditions imposed by global lenders could cause an outcry.
Lionel Messi hit a hat-trick as Barcelona warmed up for the El Clasico with Real Madrid next weekend with a 7-0 victory over Osasuna that put them four points off the top of La Liga.
Williams, who played an exhibition match last December in the United Arab Emirates, where she lost to French Open champion Jelena Ostapenko, said in addition to working on her serve and returns, she needs to manage her time better now that she has her daughter in tow.
Marcus Rashford scored twice as holders Manchester United brushed aside second-tier Burton Albion 4-1 at Old Trafford to reach the fourth round of the League Cup on Wednesday.
A lot of history was made on Emmys night!
The International Olympic Committee (IOC) on Tuesday mourned the death of three French sports stars, including two Olympic medallists, in a helicopter accident during the filming of a reality show.
Check out the 10 most expensive transfers in British soccer history.
The win moved Spurs up to third but unbeaten Manchester City still looked in a class of their own at the top as Leroy Sane scored twice in a 4-0 stroll over West Ham United.
Seeing the cut on the phone cam, his pretty face damaged, the Portuguese forward's expression said it all.
Anand settled for a quick draw against Vassily Ivanchuk. He shares the lead with Judit Polgar and Evgeny Bareev.
Cristiano Ronaldo and Lionel Messi will again be duelling for the title of world's best footballer after their names once again headed the shortlist on Thursday for The Best FIFA Men's Player.
A look at the glamorous brigade on the red carpet.
FA Cup winners Arsenal beat champions Chelsea 1-0 in England's Community Shield season curtain-raiser at Wembley on Sunday to end a long wait for victory over their London rivals.
Sanchez, 28, is currently in the final year of his contract. He has been linked with a move to Paris St Germain in the current transfer window.
Alexis Sanchez had equalised for the visitors, scoring on the rebound after Manuel Neuer saved his 30th-minute penalty but the Gunners suffered when captain Laurent Koscielny limped off injured to leave the defence exposed.
Images from the FA Cup matches played on Saturday
Serena Williams clinched a record 23rd grand slam title at the Australian Open on Saturday but spent most of the immediate aftermath talking about her older sister Venus.
Stress makes your scalp weak and gives hair breakage. Try to stay happy.
And, since, pictures speak more than words, Rediff.com brings you images from these sporting events and others that made headlines in the week gone by.
The start to the 13 Tests long season could not have been better for India. A convincing win in their 500th Test over New Zealand with spinners Ravichandran Ashwin and Ravindra Jadeja weaving their magic on a turning track to hand India a 1-0 lead in the three-match Test series. Pakistan captain Misbah-ul-Haq receiving the Test mace for their meteoric rise to No.1 ranking in cricket's traditional format. Also, football took precedence once again, a struggling Manchester United ran riot at Old Trafford as they beat Premier League champions Leicester 4-1. An outstanding first-half performance by Arsenal helping them beat London rivals Chelsea. Other top teams like Manchester City and Liverpool also taking full points.
India's software and engineering exports may take a hit and the country may also face larger capital outflows.
Chile bundled reigning champions Uruguay out of the Copa America with a 1-0 victory.
Liverpool and champions Manchester City drew 0-0 at Anfield while Chelsea and Arsenal enjoyed comfortable away wins. City are top on goal difference from Liverpool and Chelsea with Arsenal two points behind.
Photos from the English Premier League match played between Manchester United and Arsenal on Saturday
Second-half goals from Arturo Vidal and Eduardo Vargas gave hosts Chile a 2-0 victory over Ecuador.
Following is a match by match look at the English Premier League's weekend fixtures:
Leicester City were left in touching distance of a fairytale first Premier League title on Sunday after Leonardo Ulloa's double helped them outclass Swansea City at a delirious King Power Stadium.
League leaders Chelsea were made to battle for a narrow 2-1 win over strugglers Queens Park Rangers at Stamford Bridge as they maintained their unbeaten start in the Premier League on Saturday.
Williams, a record 23-times Grand Slam champion, will be returning to the All England Club for the first time since giving birth to her daughter last September.
Six-time champions and title holders Germany continued their fine form and defeated New Zealand 2-1 in a closely-fought Pool C encounter to virtually seal their place in the quarter-final of the men's Junior Hockey World Cup, in Lucknow on Friday.
A downbeat Arsene Wenger said he has decided on his Arsenal future and would reveal all soon after his side slumped to a dismal 3-1 defeat at West Bromwich Albion on Saturday.
Arsenal missed the chance to heighten the congestion at the top of the Premier League and suffered fresh injury blows when a frustrating 1-1 draw at Norwich City failed to take them alongside leaders Manchester City and Leicester City on Sunday.
Swansea City came from behind to beat Arsenal 2-1 and Tottenham Hotspur's misery continued with a 2-1 home defeat by Stoke City, making it a nightmare Sunday for north London.
America's chances of hosting the 2026 World Cup are not likely to be hurt by a US led corruption investigation that has ensnared key figures in FIFA, world soccer's governing body, analysts said on Thursday.
Kazakh weightlifter Zulfiya Chinshanlo broke her own clean and jerk world record in the 53kg category at the Asian Games on Sunday, but it was not enough to snatch gold from Taiwan's Hsu Shu Ching, who also set a new combined world mark of 233kg.
India's bid for a permanent seat in a reformed United Nations Security Council has received a strong support from many UN member states, including the UK and France, who emphasised that the the world body's top organ must reflect the emergence of new global powers.