Rain is expected to play role in 5th ODI in Thiruvananthapuram even as the wicket-keeper batsmen will look to complete 10,000 ODI runs.
India go into the final ODI on Thursday eyeing another home series triumph against the West Indies, a far cry from the dominant force it was when the city last hosted a 50-over international three decades ago.
A victory in the fifth and penultimate One-day International in Thiruvananthapuram will ensure India maintain their unbeaten run since the reverse against South Africa in 2015.
Leading 2-1 in the five-match series that also witnessed a tie, the hosts faced unexpected resistance in the past few days, including suffering a shock defeat, since the time the West Indians set foot in the country a little more than a month ago.
The weather is expected to play a part with showers predicted.
Virat Kohli's men bounced back from the loss in the third match at Pune to record a massive 224-run win in Mumbai.
The home team will hope to carry the momentum into the series decider in the Southern city.
The last ODI played here was also between the two teams and was won by the visiting side, then an eminent force in world cricket.
Jason Holder's men will look to seek inspiration from their illustrious predecessors and level the series.
With the series being the first in the run-up to the 50-overs World Cup in England in June next year, the two sides are more or less aiming to zero in on their team combinations for the showpiece tournament.
While Kohli and Rohit Sharma have been in superlative form, scoring three and two centuries respectively, Ambati Rayudu, backed by the skipper, has also been among the runs.
The rest of the batsmen haven't quite had the impact they would have liked to. The flamboyant Shikhar Dhawan has not capitalised on the starts while veteran Mahendra Singh Dhoni has found runs hard to come by.
Left out of the T20 squad for the upcoming series in Australia, the Jharkhand stumper will hope to make a contribution in front of the stumps, too, even though his work with the big gloves has been stupendous.
The return of Jasprit Bumrah has added value to the Indian team and he proved his worth in the two games he has played while the young Khaleel Ahmed showed he's learning with an impressive spell at the Brabourne Stadium.
Kohli will expect the experienced Bhuvneshwar Kumar to raise his level of play in the series finale after moderate returns. The seamer has been recalled following a rest.
The spinners have done the damage with most of the Caribbean batsmen struggling to cope with Kuldeep Yadav, while Yuzvendra Chahal was benched for the fourth ODI in favour of Ravindra Jadeja.
The visitors, on the other hand, have blown hot and cold in the one-dayers after being routed in the Tests.
Shimron Hetmyer and Shai Hope have impressed the most, having logged a century each while underlining their abilities. Captain Holder has shown he can handle the Indian spinners pretty well but the other batsmen have failed to fire.
Holder will be hoping that the team improves collectively to snatch a win and deny India a series triumph.
It is easier said than done but the young West Indies squad has shown they have the talent but not the requisite temperament.
The participation of off-spinner Ashley Nurse, who has been a consistent performer, is in doubt after he suffered an injury during the Mumbai game. His absence could affect the hopes of the Windies in the all-important game.
The final ODI, the second international game to be played at the new Greenfield Stadium in Thiruvananthapuram, is expected to draw a full house but the weather holds the key.
India: Virat Kohli (captain), Rohit Sharma (vice-captain), Shikhar Dhawan, Ambati Rayudu, Rishabh Pant, MS Dhoni (wicketkeeper), Kedar Jadhav, Ravindra Jadeja, Kuldeep Yadav, Yuzvendra Chahal, Bhuvneshwar Kumar, Jasprit Bumrah, Khaleel Ahmed, Umesh Yadav, Lokesh Rahul, Manish Pandey.
West Indies: Jason Holder (captain), Fabian Allen, Sunil Ambris, Devendra Bishoo, Chanderpaul Hemraj, Shimron Hetmyer, Shai Hope (wicketkeeper), Alzarri Joseph, Evin Lewis, Ashley Nurse, Keemo Paul, Rovman Powell, Kemar Roach, Marlon Samuels, Oshane Thomas.
Match starts at 1:30 PM