Two Pakistanis were killed and an American injured in the first ever border clash between US and Pakistani forces near the Afghan village of Sikhin in which an American F-16 dropped a bomb hitting a seminary on the Pakistani side, the Washington Times reported on Wednesday, quoting a military statement.

The gunbattle between the American and Pakistani forces began on Sunday when a Pakistani border guard fired on the Americans during a disagreement on a mission being conducted with the Pakistani forces.

"A Pakistani Border Scout opened fire with a G3 rifle after a US patrol asked him to return to the Pakistani side of the border," a US military statement said on Tuesday.

The Americans ended the skirmish by dropping a 500-pound bomb from an F-16 which hit a seminary where the scouts had taken refuge, killing two of them, the report said.

"That individual and several others retreated to a nearby structure. Close air support was requested and one 500-lb bomb was dropped on the target area," the statement said adding one American soldier was injured and two members of the Pakistani Border Scouts were killed.

Media reports quoted witnesses and local officials as saying the bomb hit a seminary in Burmol village in the Waziristan tribal area in Pakistan.

The US statement did not give details of the joint US-Pakistani mission or say whether it was taking place inside Afghanistan or Pakistan.

US forces are in the area (in Afghanistan) looking for Al Qaeda fugitives but do not cross into Pakistani territory, the paper said.

PTI