The top seeded pair of Rohan Bopanna and Aisam-ul-haq Qureshi made a shock exit from the ATP Eastbourne event, suffering a straight-set defeat in the doubles quarter-finals.
Bopanna and Qureshi, winners of last week's Gerry Weber Open, lost 5-7, 3-6 to the unseeded combination of Grigor Dimitrov of Bulgaria and Italian Andreas Seppi.
With this defeat, the Indian challenge ended in the event, the last warm-up tournament before the grass court Wimbledon championships.
Bopanna and Qureshi could convert just one of the four break-points in the first set and none of two in the second set.
Somdev Devvarman and Sania Mirza had already crashed out of their respective events.
Sania could not make the singles main draw, and she and Elena Vesnina of Russia lost in the first round of the women's doubles.
Somdev reached second round in singles but lost the men's doubles opener, partnering Mark Knowles.
Somdev, who stunned fourth seed Guillermo Garcia-Lopez of Spain 6-3, 6-4 in the first round, fought hard before going down 6-7(1), 7-6(6), 3-6 to Julien Benneteau of France in a round of 16 clash that lasted little more than two-and-a-half hours.
Third seeded pair of Sania and Elena lost 7-5, 4-6, 6-10 to the unseeded Australian duo of Samantha Stosur and Jarmila Gajdosova.