Goals from Jan Vertonghen and Jermain Defoe left Tottenham Hotspur on the cusp of the Europa League knockout stages as four other clubs maintained perfect starts on Thursday.
Fiorentina, Salzburg, Eintracht Frankfurt and Ludogorets joined Spurs on nine points from three games with a place in the last 32 beckoning.
Twice UEFA Cup winners Sevilla needed a late goal to take a point at Slovan Liberec but La Liga rivals Valencia continued their recovery after an opening defeat by thumping St Gallen 5-1.
Defoe, with his sixth Europa League goal in four games, equalled Martin Chivers' club European record of 22 for Spurs with the second goal in a 2-0 win in Moldova over Sheriff Tiraspol.
Former England striker Chivers was part of Spurs' UEFA Cup-winning side of 1972.
Spurs could have qualified for the last 32 with three group games still to play but needed Anzhi Makhachkala and Tromso to draw in the other Group K game. Anzhi won 1-0, though, to leave Spurs waiting a bit longer.
Vertonghen headed home Christian Eriksen's 12th-minute cross and Defoe struck from 25 metres with 15 minutes remaining.
Substitute Victor Machin equalised two minutes from time as Sevilla salvaged a 1-1 draw against Slovan Liberec in the Czech Republic to stay top of Group H with seven points.
The hosts led through Michael Rabusic's first-half goal but had goalkeeper Premysl Kovar dismissed on 78 minutes and Machin rounded his replacement Lukas Hrosso to level late on.
Valencia, UEFA Cup winners in 2004, ran riot in the first half against St Gallen at Mestalla, Argentine Federico Cartabia scoring two of four first-half goals.
The Spaniards moved on to six points in Group A, one behind Swansea City who conceded a penalty in stoppage time that secured Kuban Krasnodar a 1-1 draw in Wales.
Fiorentina, fresh from a remarkable fightback from 2-0 down to beat Juventus 4-2 in Serie A on Sunday, brushed aside Romania's Pandurii 3-0 in Group E while Salzburg continue to impress.
They set a record of 31 games unbeaten in the Austrian Bundesliga at the weekend and got the better of a feisty Group C encounter with Standard Liege in which three players saw red.
Salzburg, who won 2-1 thanks to goals from Jonathan Soriano and Ramalho, had Sadio Mane sent off late in the first half, shortly after Mehdi Carcela-Gonzalez was dismissed for Liege.
The Belgians were reduced to nine men on 67 minutes when Brazilian defender Kanu was shown a straight red.
Lazio relinquished top spot in Group J to Trabzonspor after the Italian side could only draw 0-0 away at Apollon Limassol. Trabzonspor, who eased to a 2-0 win at home over Legia Warsaw, have seven points to Lazio's five.
A second-half goal from Clement Grenier handed Olympique Lyon their first Group I win after two draws, the French side edging Rijeka 1-0 to move on to five points, along with Real Betis who beat Vitoria Guimares by the same scoreline.
An extraordinary match in Salonika saw hosts PAOK concede twice in the first 21 minutes, miss two penalties with Miroslav Stoch wasting both and still run out 3-2 winners to take control of Group L.
Haifa were 2-0 up through Dino Ndlovu and Eyal Golasa before Miguel Vitor pulled one back.
Stoch had his first spot-kick saved by Bojan Saranov before atoning by setting up Sotiris Ninis to level.
Slovakian international Stoch then had another penalty saved by Saranov just before halftime but his blushes were spared when Dimitros Salpingidis volleyed in the winner at the near post on 66 minutes.
Eintracht, 2-0 winners at home to Maccabi Tel Aviv, hold a five-point lead in Group F while Bulgarian champions Ludogorets won 1-0 at Chernomorets Odessa to lead PSV Eindhoven by five points in Group B.
Image: Tottenham Hotspur's Jermain Defoe celebrates his goal during the Europa League soccer match against Sheriff Tiraspol in Tiraspol, on Thursday
Photograph: Gleb Garanich/Reuters