World number one Rafael Nadal begins his French Open title defence, on Monday, with a clash against Italy's Simone Bolelli on Court Philippe-Chatrier.
Novak Djokovic, looking to get back to winning ways on the biggest stage following elbow surgery, takes on unseeded Brazilian Rogerio Dutra Silva.
Dominic Thiem, one of the players capable of denying Spaniard Nadal a record-extending 11th title at Roland Garros, opens his campaign on Court One against Ilya Ivashka of Belarus.
Five-times grand slam champion Maria Sharapova is also in action, with the Russian taking on Richel Hogenkamp of the Netherlands on Court Suzanne-Lenglen.
Order of play on the main showcourts (all matches first round, times GMT, prefix numbers denote seeding):
Court Philippe-Chatrier (play starts at 0900)
8-Petra Kvitova (Czech Republic) v Veronica Cepede Royg (Paraguay)
Rogerio Dutra Silva (Brazil) v 20-Novak Djokovic (Serbia)
Danielle Collins (U.S.) v 2-Caroline Wozniacki (Denmark)
1-Rafael Nadal (Spain) v Simone Bolelli (Italy)
Court Suzanne-Lenglen (0900)
Guillermo Garcia-Lopez(Spain) v 23-Stan Wawrinka (Switzerland)
Andrea Petkovic (Germany) v 29-Kristina MLADENOVIC (France)
Andreas Seppi (Italy) v 27-Richard Gasquet (France)
28-Maria Sharapova (Russia) v Richel Hogenkamp (Netherlands)
Court 1 (0900)
Benoit Paire (France) v Roberto Carballes Baena (Spain)
7-Dominic Thiem (Austria) v Ilya Ivashka (Belarus)
Laura Siegemund (Germany) v 15-Coco Vandeweghe (U.S.)
Barbora Krejcikova (Czech Republic) v 6-Karolina Pliskova (Czech Republic)