A 14-year-old disgruntled student went on shooting spree in his high school in Cleveland, Ohio injuring five people before turning the gun on himself.
Two revolvers along with three knives and a box of ammunition were found near the body of suspended student Asa Coon who had walked through the halls firing from the weapons, one in each hand.
Cleveland Police Chief Michael McGrath said he did not believe it was a random shooting and some of the victims were specifically targeted by the teenager.
Coon, who was suspended on Monday apparently for fighting, might have gone looking for teachers who had disciplined him.
Among the victims were 57-year-old teacher David Kachadourian who was shot in the back and a 42-year-old teacher who was struck in the chest, officials said, adding three other victims were students.
Screaming students ran for cover after the Principal announced "Code Blue" on the intercom which meant there was shooting in the school.
Coon was previously arrested last year for a domestic violence incident, and police had been to his home before for incidents that involved weapons, according to McGrath.
Police searched the gunman's locker after the shooting and are watching surveillance footage of the school taken at the time of the shooting, he said.
It is the latest school shooting to hit the US which has witnessed several such incidents in recent years leading to an outcry against lax gun-control rules.
Last month two University students were shot in Delware while in April, over 30 people, including an Indian professor and a student, were killed in a college shooting in Virginia.
In October last year, a 32-year-old gunman shot dead five girls at an Amish school in Pennsylvania, before killing himself. A month earlier, a gunman in Colorado shot and fatally wounded a teenage schoolgirl, then killed himself.
In March 2005, a Minnesota schoolboy killed nine people before shooting himself while in 1999, two students killed 13 people in the Columbian High School in Colorado.
